What is EMDA®
EMDA®, Electromotive Drug Administration, is a device-assisted therapy that increases drug transport across biological membranes under the influence of an electric field
EMDA® is characterized by a combination of different electromolecular interactions that improve drug absorption from 4 to 7 times:
The deeper drug penetration and the greater drug bioavailability result in an increased clinical effectiveness
EMDA® treatment is quick, easy to use and safe
A unique technology to augment the effect of intravesical chemotherapy by creating an electric field across the bladder wall which increases urothelium’s permeability
Electromotive drug administration
The efficacy of MMC using electromotive drug administration (EMDA) sequentially combined with BCG in
patients with high-risk tumours has been demonstrated in one small RCT . The definitive conclusion,
however, needs further confirmation. For application of device-assisted instillations in patients recurring after
BCG treatment, see Section 7.9.3.
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INTERMEDIATE-RISK NON-MUSCLE INVASIVE BLADDER CANCER
SINGLE INTRAVESICAL INSTILLATION OF EMDA-MITOMYCIN BEFORE TURBT
INTRAVESICAL SEQUENTIAL ADMINISTRATION OF BCG AND EMDA-MITOMYCIN IN HIGH-RISK NMIBC
BCG FAILURE PATIENTS
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