Electromotive Drug Administration

What is EMDA®

EMDA® is a device-assisted therapy that increases drug transport across biological membranes under the influence of an electric field

EMDA® is characterized by a combination of different electromolecular interactions  that  improve drug absorption from 4 to 7 times:

  • Iontophoresis
  • Electrophoresis/Electroosmosis
  • Electroporation

The deeper drug penetration and the greater drug bioavailability result in an increased clinical effectiveness

EMDA Pain Therapy Protocols

PHYSION’s CT-DAS skin electrodes are used in ElectroMotive Drug Administration (EMDA®) drug delivery, which is an innovative and effective method to induce a high local concentration of a drug with a negligible plasmatic level.
EMDA® uses electricity (in the mA range) to provide “active,” non-invasive delivery that can make a large amount of drug molecules penetrate the tissues, thus creating a high local concentration.
The depth reached by the drug in the tissues can be controlled by factors such as the molecular weight of the drug, the width of the area to be treated, the intensity of the current, and the duration of the treatment.
The EMDA® system thus removes some of the limitations related to systemic administration and allows a high concentration of drugs at the disease site.
Our protocols cover the following therapies: ANTIBACTERIAL, ANTI-INFLAMMATORY, ANTIMYCOTIC, LOCAL ANESTHESIA and SPECIFIC THERAPIES such as RSD (Reflex Sympathetic Dystrophy).

Nerve Entrapment - Inflammation

  • Elbow and ulnar nerve entrapment
  • Carpal tunnel syndrome
  • Wrist- Guyon’s canal syndrome
  • Radial-cubital syndrome
  • Crural tunnel and thigh syndrome
  • Tarsal canal syndrome (Foot)
  • Metatarsal canal syndrome (Foot)

Musculoskeletal Inflammation

  • Local anti-inflammatory therapies in general.
  • Rheumatoid arthritis
  • Psoriatic arthropathy
  • Ankylosing spondylitis
  • Arthrosis in general
  • District osteoporosis and fracture-welding defects

RSD Reflex Sympathetic Dystrophy

Post Herpetic Neuropathy

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